Research For better living

Product: TIM services

As part of oral drug development, reliable scientific data about the transit through the gastrointestinal tract is needed, preferably in a time- and cost-efficient way. Triskelion fulfills these requirements by offering gastrointestinal testing with the TNO gastroIntestinal Models (TIM). The TIM-1 and tiny-TIM systems simulate the dynamic conditions in the stomach and small intestine, whereas the TIM-2 system simulates the large intestine.
In current pharmaceutical research the increasing extent of challenging compounds for oral delivery and maintained high interest in Modified Release products are prompting a growing need for reliable predictive tools. In addition, numerous bioavailability and bioequivalence studies fail during the late phase of drug development. The TIM systems improve the success rate of clinical trials by selecting the most promising candidate and optimum test conditions.