Research For better living

category: News item

Continuation of (bio)analytical studies under GLP

Following our previous announcement on Triskelion’s altered services portfolio, we would like to give you an update on the latest development.

We are pleased to inform you that Triskelion has decided to continue the performance of (bio)analytical studies under GLP. As such we are still able to ensure and deliver services with the highest applicable standards (GLP and ISO 17025 quality and expertise).

We are looking forward to present to you our new strategy by the end of 2018.

At this moment we continue to deliver best in class solutions in the area of:

  • Nutrient analyses
  • Genetically modified Organisms (GMO) analyses
  • Authenticity analyses
  • Emergency Response Service (ERS)
  • Registration Services & Risk Assessment
  • Packaging (migration, petitioning and compliance)
  • TIM: gastrointestinal models (services & lease)
  • (Bio) analytical services (GLP and non-GLP): method development, validation and sample analyses

We are happy to discuss your current and future needs.

Might you have any queries or questions, please feel free to contact us:

Join upcoming TIM lab days – Q4 2018 or spring 2019

We would like to ask your attention for our upcoming TIM lab days. During these days, we will showcase the newest TIM technology additions like the new stomach compartment and new TIM table top model at our facilities in Zeist, The Netherlands. During these TIM lab days you will get a deeper understanding of the use and capabilities of our TIM technology. To see more of our TIM models, please click here.

We would very much like to learn if this is of any interest to you. If so, would you please be so kind to let us know your availability during the last quarter of 2018 or spring of 2019?

Please send an email with the dates of your preference to with the following subject note: ‘availability TIM lab days’.

We look forward to receiving your positive feedback and welcoming you to our TIM lab days.

If you would like to receive additional information, pelase do not hesitate to contact us via e-mail or phone +31 (0)6 5280 3578.

Successful submission of all dossiers before REACH deadline

We proudly announce that the Registration Services & Risk Assessment team of Triskelion enabled all of their REACH clients to comply with the 3 major legal deadlines in 2010, 2013 and 2018.

Years of helping clients with their registration strategies, data gap analyses, SIEF discussions, pushing for early action, outsourcing and monitoring studies, creating IUCLID files, preparing read-across justifications and exposure assessments paid off as we were able to send the final files and dossiers to the clients well before the final deadline of 31 May 2018.

By focusing on being proactive, applying strong project management techniques and putting our experience collected through years of service into practice, unpleasant surprises were kept to a minimum.

For substances with ongoing studies we ensured eligibility for the Directors Contact Group solutions. Our structured approaches and familiarity with relevant tools ensured that we could finalize quality dossiers in time.

All in all, thanks to good preparation and experience we were able to make our clients happy, delivering a few hundred high-quality REACH dossiers ranging from relatively simple dossiers  to very large dossiers with lots of data or extensive use of read-across and other alternative approaches. Simultaneously with these activities, we were also meeting the needs of our clients in the scope of the Biocidal Products Regulation.

And, of course, the REACH-related activities continue: dossiers have to be updated and resubmitted, the communication with ECHA on (draft) decisions and approval of test proposals continues, downstream user communication is getting more attention and clients need support in the scope of restriction or authorization processes.

We look back on fruitful and successful cooperation with our clients before the REACH deadline and we look forward to continuing our support for the chemical industry with our regulatory services in the future.

Triskelion’s transition plans and altered services portfolio as of January 1, 2019

Taken into consideration the current technical developments on pharma, food and chemical testing in combination with the Dutch and EU governmental desire to reduce animal use in testing, Triskelion has decided to redirect its focus on analytical and registration services. We will therefore discontinue our animal related services as of January 1, 2019. We will finish the ongoing projects in accordance with the quality standards as promised.

We would like to emphasize that our decision does not affect the animal related research activities of TNO (, the organization from which Triskelion originates.

The following services will no longer be offered as of January 1, 2019:

Toxicology (in vivo and in vitro)
Immunology (in vivo and in vitro)
ADME/DMPK (in vivo and in vitro)

We will focus on delivering best in class solutions in the area of

Nutrient analyses
Genetically modified Organisms (GMO) analyses
Authenticity analyses
Emergency Response Service (ERS)
Registration Services & Risk Assessment
Packaging (migration, petitioning and compliance)
TIM: gastrointestinal models (services & lease)
(Bio) analytical services (GLP and non-GLP): method development, validation and sample analyses

Triskelion takes pride in being your trusted partner in these fields of expertise. We will ensure to deliver the altered services portfolio to the highest standards applicable. During the coming months we will inform you about the next steps we will take in building our altered services portfolio. Please check our website for available updates.

Might you have any questions, please feel free to contact us:

New FAO recommendation of protein quality measurement DIAAS

To meet the protein requirements of its growing population, the world must discover new alternative protein sources. It is therefore essential to understand the value and consequent suitability of these proteins for human nutrition.

The FAO recommends the use of the Digestible Indispensable Amino Acid Score (DIAAS) method instead of the PDCAAS measurement. The DIAAS is based on the true ileal digestibility of each amino acid preferably measured in humans or animal models. The Three Rs (3Rs) principle, the guiding principle for more ethical use of animal testing, is one of the corporate responsibilities of the food industry. So are you ready for DIAAS without expensive clinical or animal trials?

Triskelion has developed an in vitro method which allows rapid and cost-effective evaluation of both, the true ileal digestibility and the DIAAS method. Our unique dynamic in vitro gastrointestinal model tiny-TIM simulates the dynamic conditions of the upper tract. DIAAS can be accurately and reliably determined in the TIM system (Havenaar et al 2016). The dynamic gastrointestinal TIM models are a validated alternative for animal testing.

If you are interested in speeding up your product development process, please contact us:
We would be more than happy to give you more information.