General Toxicology and Pharmacology
TNO Triskelion specialises in toxicology and pharmacology solutions for new pharmaceutical products, including biologicals, small molecules and pharmabiotics. Our mission is to help your product be first for human intake and beyond by offering the best preclinical service possible.TNO Triskelion offers the preclinical support that adds value. We commit to superior study design, quality and prompt delivery of results, all in close collaboration with you. We specialise in:
- Immunotoxicology and cardiovascular safety in minipigs
- Inhalation toxicology of nanoparticles and drug mixtures
- Toxicity testing of GMO’s and genetherapy products under BSL-2 conditions in full GLP compliance
- Incorporation of pharmacology endpoints in (geno)toxicity studies and vice versa
- Pharmaco- & toxicokinetic support for (bio)pharmaceuticals and bioanalytics
- Toxicological support for Exploratory Clinical Trials (microdosing)
Toxicology services
Backed by 40 years of experience with species like rat, mouse, rabbit, guinea pig, hamster, dog, minipig and goat, TNO Triskelion offers toxicology services for your preclinical needs:
- Local tolerance
- Dose Range Finding and MTD
- Single and repeated dose toxicity
- Carcinogenicity
- Safety pharmacology
- Genotoxicity
- Reproduction toxicity
- mmunotoxicity
- Neurotoxicity
- Photosafety
- Tumorigenicity
- Experimental tumour models